1. Maletic-Savatic M, Lenn NJ, Trimmer JS. (1995) Differential spatiotemporal expression of K+ channel polypeptides in rat hippocampal neurons developing in situ and in vitro. J Neurosci 15: 3840-3851. PMID: 7751950
  2. Maletic-Savatic M, Malinow R. (1998) Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part I: Trans-Golgi network-derived organelles undergo regulated exocytosis. J Neurosci 18: 6803-6813. PMID: 9712651
  3. Maletic-Savatic M, Koothan T, Malinow R. (1998) Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part II: Mediation by calcium/calmodulin-dependent protein kinase II. J. Neurosci. 18: 6814-6821. PMID: 9712652
  4. Mainen ZF, Maletic-Savatic M, Shi SH, Hayashi Y, Malinow R, Svoboda K. (1999) Two-photon imaging in living brain slices. Methods (San Diego, Calif.) 18: 231-239. PMID: 10356355
  5. Maletic-Savatic M, Malinow R, Svoboda K. (1999) Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity. Science 283: 1923-1927. PMID: 10082466
  6. Nasr J, Gabis L, Maletic-Savatic M, Andriola M. (2001) The Electroencephalogram in Children with Developmental Dysphasia. Epilepsy and Behav 2: 115-118. PMID: 12609193
  7. Manganas L, Maletic-Savatic M. (2005) Stem Cell Therapy for CNS Demyelinating Diseases. Curr Neurol Neurosci Rep 5(3): 225-231. PMID: 15865888
  8. Mignone JL, Roig-Lopez JL, Fedtsova N, Schones DE, Manganas LN, Maletic-Savatic M, Keyes WM, Mills AA, Gleiberman A, Zhang MQ, Enikolopov G. (2007) Neural Potential of a Stem Cell Population in the Hair Follicle. Cell Cycle 6(17): 2161-2170. PMID: 17873521
  9. Manganas L, Zhang S, Li Y, Hazel R, Smith D, Wagshul M, Henn F, Benveniste H, Djuric P, Enikolopov G, Maletic-Savatic M. (2007) Magnetic Resonance Spectroscopy identifies neural progenitor cells in the live human brain. Science 318: 980-985. PMID: 17991865
  10. Maletic-Savatic M, Vingara LK, Manganas LM, Li Y, Zhang S, Sierra A, Hazel A, Smith D, Wagshul ME, Henn F, Krupp L, Enikolopov G, Benveniste H, Djuric PM, Pelczer I. (2008) Metabolomics of neural progenitor cells: A novel approach to biomarker discovery. Cold Spring Harb Symp Quant Biol 73: 389-401. PMID: 19022759
  11. Djuric P, Wagshul M, Henn F, Benveniste H, Enikolopov G, Maletic-Savatic M. (2008) Response to Comments on “Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain”. Technical Report, Science 321: 640. PMID: 26380846
  12. Malinow R, Hayashi Y, Maletic-Savatic M, Zaman SH, Poncer JC, Shi SH, Esteban JA, Osten P, Seidenman K. (2010) Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection. Cold Spring Harb Protoc 2010(4): 5406. PMID: 20360360
  13. Sierra A, Encinas JM, Deudero JJ, Chancey JH, Enikolopov G, Overstreet-Wadiche LS, Tsirka SE, Maletic-Savatic M. (2010) Microglia shape adult hippocampal neurogenesis through apoptosis-phagocytosis coupling. Cell Stem Cell 7(4):483-495. PMID: 20887954
  14. Ma LH, Li Y, Djurić PM, Maletić-Savatić M. (2011) Systems biology approach to imaging of neural stem cells. Methods Mol Biol 711: 421-434. PMID: 21279615
  15. Sierra A, Encinas JM, Maletic-Savatic M. (2011) Adult human neurogenesis: from microscopy to magnetic resonance imaging. Front Neurosci 5: 47. PMID: 21519376
  16. Allen GI, Maletic-Savatic M. (2011) Sparse Non-Negative Generalized PCA with applications to metabolomics. Bioinformatics 27(21): 3029-3035. PMID: 21930672
  17. Yu HJ, Christodoulou C, Bhise V, Greenblatt D, Patel Y, Serafin D, Maletic-Savatic M, Krupp LB, Wagshul M. (2012) Multiple white matter tract abnormalities underlie cognitive impairment in RRMS. Neuroimage 59(4): 3713-3722. PMID:22062194
  18. Abraham AB, Bronstein R, Reddy AS, Maletic-Savatic M, Aguirre A, Tsirka SE. (2013) Aberrant neural stem cell proliferation and increased adult neurogenesis in mice lacking chromatin protein HMGB2. PLos One 8(12): e84838. PMID: 24391977
  19. Abraham AB, Bronstein R. Chen EI, Koller A, Ronfani L, Maletic-Savatic M, Tsirka SE. (2013) Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells. Proteome Sci 11(1): 18. PMID: 23621913
  20. Allen GI, Peterson C, Vannucci M, Maletic-Savatic M. (2013) Regularized partial least squares with an application to NMR spectroscopy. Stat Anal Data Min 6(4): 302-314. PMID: 24511361
  21. Wiszniewski W, Hunter JV, Hanchard NA, Willer JR, Shaw C, Tian Q, Illner A, Wang X, Cheung SW, Patel A, Campbell IM, Gelowani V, Hixson P, Ester AR, . . . Maletic-Savatic M, Rosenfeld JA, Shaffer LG, Davis EE, Belmont JW, Dunstan S, Simmons CP, Bonnen PE, Leal SM, Katsanis N, Lupski JR, Lalani SR. (2013) TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. Am J Hum Genet, 93(2): 197-210. PMID: 23810381
  22. Peterson C, Vannucci M, Karakas C, Choi W, Ma L, Maletic-Savatic M. (2013) Inferring metabolic networks using the Bayesian adaptive graphical lasso with informative priors. Stat Interface 6: 547-558. PMID: 24533172
  23. (fix)Vingara LK, Yu HJ, Wagshul ME, Serafin D, Christodoulou C, Pelczer I, Krupp LB, Maletic-Savatic M. (2013) Metabolomic approach to human brain spectroscopy identifies associations between clinical features and the frontal lobe metabolome in multiple sclerosis. Neuroimage 82: 586-594. PMID: 23751863
  24. Pati S, Supeno NE, Muthuraju S, Abdul Hadi R, Ghani AR, Idris FM, Maletic-Savatic M, Abdullah JM, Jaafar H. (2014) MicroRNA profiling reveals unique miRNA signatures in IGF-1 treated embryonic striatal stem cell fate decisions in striatal neurogenesis in vitro. Biomed Res Int 2014: 503162. PMID: 25254208
  25. Shetty AN, Chiang S, Vannucci M, Maletic-Savatic M, Lee W. (2014) Spatial Mapping of Translational Diffusion Coefficients Using Diffusion-Tensor Imaging: A Mathematical Description. Concepts in Magnetic Resonance, Part A 43 (1): 1-27. PMID: 27441031
  26. Botas A, Cambell-Moore H, Han X, Maletic-Savatic M. (2015) Metabolomics of neurodegenerative diseases. Inter Rev Neurobiol 122: 53-80. PMID: 26358890
  27. A. Erramuzpea, J.M. Encinas, A. Sierra, M. Maletic-Savatic, A.L. Brewster, A.E. Anderson, S. Stramaglia, J.M. Cortes. (2015) Longitudinal variations of brain functional connectivity in a mouse model of mesial temporal lobe epilepsy. F1000Research 4: 144. PMID: 26167275
  28. Arnold JM, Choi WT, Sreekumar A, Maletić-Savatić M. (2015) Analytical strategies for studying stem cell metabolism. Front Biology 10 (2): 141-153. PMID: 26213533
  29. Sierra A, Martín-Suárez S, Valcárcel-Martín R, Pascual-Brazo J, Aelvoet S-A, Abiega O, Deudero JJP, Brewster AL, Bernales A, Anderson AE, Baekelandt V, Maletić-Savatić M*, Encinas JM* (2015) Neuronal Hyperactivity Accelerates Depletion of Neural Stem Cells and Impairs Hippocampal Neurogenesis. Cell Stem Cell 16 (5) 488-503. * Co-senior authors PMID: 25957904
  30. Zhu Y, Fan Q, Han X, Zhang H, Chen J, Wang Z, Zhang Z, Tan L, Xiao Z, Tong S, Maletic-Savatic M, Li Y. (2015) Decreased thalamic glutamate level in un-medicated adult obsessive-compulsive disorder patients detected by proton magnetic resonance spectroscopy. J Affect Disord 178: 193-200. PMID: 25819113
  31. Pati S, Muthuraju S, Hadi RA, Huat TJ, Singh S, Maletic-Savatic M, Abdullah JM, Jaafar H. (2016) Neurogenic plasticity of mesenchymal stem cell, an alluring cellular replacement for traumatic brain injury. Curr Stem Cell Res Ther 11(2): 149-157. PMID: 26763886
  32. (fix)Irungu-Mwangi B, Cao B, Tustison NJ, Kochunov P, Maletic-Savatic M, Frye RE, Soares JC, Hasan K. (2016) Entorhinal Cortex Thickness across the Human Lifespan. J Neuroimaging 26(3): 278-82. PMID: 26565394
  33. Abiega O, Beccari S, Diaz-Aparicio I, Nadjar A, Layé S, Leyrolle Q, Gómez-Nicola D, Perry HV, Sánchez-Zafra V, Deudero JJP, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco M, Matute C, Maletic-Savatic M, Encinas JM, Sierra A. (2016) Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling. PLoS Biol 14(5):e1002466. PMID:27228556
  34. Zhang X, Tang Y, Maletic-Savatic M, Sheng J, Zhang X, Zhu Y, Zhang T, Wang J, Tong S, Wang J, Li Y. (2016) Altered neuronal spontaneous activity correlates with glutamate concentration in medial prefrontal cortex of major depressed females: An fMRI-MRS study. J Affect Disord 201: 153-161. PMID: 27235818
  35. Cvoro A, Bajic A, Zhang A, Simon M, Sieglaff DH, Maletic-Savatic M, Korac A, Webb P. (2016) Ligand independent and subtype-selective actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells. PlosOne 11(10):e0164407. PMID: 27732649
  36. Petrovchich I, Sosinsky A, Konde A, Archibald A, Henderson D, Maletic-Savatic M, Milanovic S (2016). Metabolomics in Schizophrenia and Major Depressive Disorder. Front Biol, 11(3): 222-231. PMID in process
  37. Semerci F, Maletic-Savatic M (2016).Transgenic mouse models for studying adult neurogenesis. Front Biol. 11(3): 151-167. PMID: 28473846
  38. Basch M, Brown R, Jen HI, Semerci F, Depreux F, Edlund R, Zhang H, Norton C, Gridley T, Cole S, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves A. (2016) Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. eLife 5. pii: e19921. PMID: 27966429
  39. Jiang X, Chen J, Bajić A, Zhang C, Song X, Carroll SL, Wang MC, Xue M, Schaaf C, Maletić-Savatić M, Wang J. (2017) Quantitative Real-Time Imaging of Glutathione. Nat Commun. 8: 16087. PMID: 28703127
  40. Maletic-Savatic M. (2017) A question of fate. PLoS Biol. 15(5):e2002329. PMID: 28505150
  41. Bielefeld P, Sierra A, Encinas JM, Maletic-Savatic M, Anderson A. A, Fitzsimons CP. (2017) Standardized Protocol for Stereotaxic Intrahippocampal Administration of Kainic Acid Combined with Electroencephalographic Seizure Monitoring in Mice. Front Neurosci. 11:160. PMID: 28405182
  42. Semerci F, Choi WT, Bajic A, Thakkar A, Encinas JM, Depreux F, Segil N, Groves AK, Maletic-Savatic M. (2017) Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance. eLife 6. pii: e24660. PMID: 28699891
  43. Li B, Sierra A, Deudero JJ, Semerci F, Laitman A, Kimmel M*, Maletic-Savatic M* (2017) Multitype Bellman-Harris branching model provides biological predictors of early stages of adult hippocampal neurogenesis. *Co-senior authors; BMC Syst Biol. 11(Suppl 5):90. doi: 10.1186/s12918-017-0468-3. PMID: 28984196
  44. Liu L, MacKenzie KR, Putluri N, Maletic-Savatic M, Bellen HJ. (2017) The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. Cell Metab. 26(5):719-737.e6. doi: 10.1016/j.cmet. 2017.08.024. PMID: 28965825
  45. Gandy K, Kim S, Sharp C, Dindo L, Maletic-Savatic M*, Calarge C.* (2017) Pattern Separation: A Potential Marker of Impaired Hippocampal Adult Neurogenesis in Major Depressive Disorder. * Co-senior authors. Front Neurosci. 11:571. doi: 10.3389/fnins.2017. 00571. eCollection 2017. PMID: 29123464
  46. Beccari S, Valero J, Maletic-Savatic M, Sierra A. (2017) A simulation model of neuroprogenitor proliferation predicts age-related loss of hippocampal neurogenesis but not astrogenesis. Sci Rep. 7 (1):16528 doi: 10.1038/s41598-017-16466-3. PMID: 29184142
  47. Tang C, Chen K, Bajic A, Choi WT, Baluya DL, Maletic-Savatic M. (2018) Analytical platforms and techniques to study stem cell metabolism. Methods Mol Biol 1842:265-281. PMID: 30196417
  48. Murthy KLP, Srinivasan T, Bochter MS, Xi R, Varanko AK, Tung KL, Semerci F, Xu K, Maletic-Savatic M, Cole SE, Shen X. Radical and lunatic fringes modulate notch ligands to support mammalian intestinal homeostasis. Elife. 2018 Apr 9;7. pii: e35710. doi: 10.7554/eLife.35710. PMID: 29629872
  49. Choi WT*, Tosun M*, Jeong HH*, Karakas C, Semerci F, Liu Z, Maletić-Savatić M. (2018) Metabolomics of Mammalian Brain Reveals Regional Differences. BMC Systems Biology, 12 (Suppl 8):127. PMID: 30577853
  50. Jiang X, Zhang C, Chen J, Choi S, Zhou Y, Zhao M, Song X, Chen X, Maletic-Savatic M, Palzkill T, Moore D, Wang M, Wang J. (2019) Quantitative Real-Time Imaging of Glutathione with Sub-Cellular Resolution. Antioxid Redox Signal. 30 (16):1900-1910. PMID: 30358421
  51. Chen K, Baluya D, Tosun M, Li F, Maletic-Savatic M. (2019) Imaging Mass Spectrometry: A New Tool to Assess Molecular Underpinnings of Neurodegeneration. Metabolites. 10;9 (7). PMID: 31295847
  52. Lucassen PJ, van Dam AMW, Kandel P, Bielefeld P, Korosi A, Fitzsimons CP, Maletic-Savatic M. (2019) The orphan nuclear receptor TLX: an emerging master regulator of cross-talk between microglia and neural precursor cells. Neuronal Signal 3(2): NS20180208. PMID: 32271856
  53. Tosun M, Semerci F, Maletic-Savatic M. (2019) Heterogeneity of Stem Cells in the Hippocampus, Adv Exp Med Biol 1169; 31-53. PMID: 31487017
  54. Lucassen PJ, Fitzsimons CP, Salta E, Maletic-Savatic M. (2020) Adult neurogenesis, human after all (again): Classic, optimized, and future approaches. Behav Brain Res 381; 112458-112462. PMID 31899214
  55. Diaz-Aparacio I, Paris I, Sierra-Torre V, Piaza-Zabala A, Rodriguez-Iglesias N, Marquez-Ropero M, Beccari S, Abiega O, Alberdi E, Matute C, Bernales I, Schulz A, Otrokocsi L, Sperlagh B, Happonen KE, Lemke G, Maletic-Savatic M, Valero J, Sierra A (2020) Microglia actively remodels adult hippocampal neurogenesis through the phagocytosis secretome. J Neurosci. 40(7): 1453–1482. PMCID: PMC7044727
  56. MacKenzie KR, Zhao M, Barzi M, Wang J, Bissig KD, Maletic-Savatic M, Jung SY, Li F (2020) Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine. Eur J Pharm Sci. 153:105488. PMID: 32712217
  57. Semerci F, Parkitny L, Maletic-Savatic M. (2021) Mouse models for studying hippocampal adult neural stem cell biology, Mouse Genetics: Methods and Protocols, 2nd edition, Springer. 2224:61-74. PMID: 33606206
  58. Manganas LN, Durá I, Osenberg S., Semerci F., Tosun M., Mishra R., Parkitny L., Encinas JM, Maletic-Savatic M (2021). BASP1 Labels Neural Stem Cells in the Neurogenic Niches of Mammalian Brain. Sci Rep. 11(1):5546. PMID: 33692421
  59. Parkitny L, Maletic-Savatic M.Glial PAMPering and DAMPening of Adult Hippocampal Neurogenesis. Brain Sci. 2021 Sep 29;11(10):1299. doi: 10.3390/brainsci11101299. PMID: 34679362
  60. Valenzuela M, Bartres-Faz D, Bullmore E, Fjell A, Maletic-Savetic M, Martins R, Solowij N, Yücel M. (2013) More thinking about less data: a perspective from the 2nd Provence Summer Workshop. Mol Psych 18(5): 524-525. PMID: 23478747
  61. Maletic-Savatic M, Valenzuela M (2016). Adult neurogenesis in Provence: Where history meets science. Front Biol, 11(3): 149-150.
  62. Sahin M, Jones SR, Sweeney JA, Berry-Kravis E, Connors BW, Ewen JB, Hartman AL, Levin AR, Potter WZ, Mamounas LA. and the Biomarker Workshop Faculty (2018) Discovering translational biomarkers in neurodevelopmental disorders. Nat Rev Drug Discov. Dec 20, PMID: 30936503
  63. Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Jiménez-Panizo A, Chamakuri S, Raji IO, Chang L, Fuentes-Prior P, MacKenzie KR, Benn CL, Estébanez-Perpiñá E, Venken K, Moore DD, Young DW, Maletic-Savatic M. (2022) Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 119(13):e2023784119 PMID: 35333654
  64. Spruill ML, Maletic-Savatic M, Martin H, Li F, Liu X. (2022) Spatial analysis of drug absorption, distribution, metabolism, and toxicology using mass spectrometry imaging. Biochem Pharmacol. 201:115080. PMID: 35561842
  65. McNerlin, C., Guan, F., Bronk, L., Lei, K., Grosshans, D., Young, D. W., Gaber, M. W., & Maletic-Savatic, M. (2022). Targeting hippocampal neurogenesis to protect astronauts’ cognition and mood from decline due to space radiation effects. Life Sciences in Space Research, 35, 170–179.
  66. Bokhari, R. S., Beheshti, A., Blutt, S. E., Bowles, D. E., Brenner, D., Britton, R., Bronk, L., Cao, X., Chatterjee, A., Clay, D. E., Courtney, C., Fox, D. T., Gaber, M. W., Gerecht, S., Grabham, P., Grosshans, D., Guan, F., Jezuit, E. A., Kirsch, D. G., … Donoviel, D. (2022). Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. Life Sciences in Space Research, 35, 105–112.
  67. Wang L, Maletic-Savatic M, Liu Z (2022) Region-specific denoising identifies spatial co-expression patterns and intra-tissue heterogeneity in spatially resolved transcriptomics data. Nat Commun. 13(1):6912. PMID: 36376296
  68. Sun J, Osenberg S, Irwin A, Ma LH, Lee N, Xiang Y, Li F, Wan YW, Park IH, Maletic-Savatic M*, Ballas N* (2023) Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular features of human astrocytes during their maturation, Cell Rep. 42(1):111942. PMID: 36640327 

Neurogenic plasticity of mesenchymal stem cell, an alluring cellular replacement for traumatic brain injury

Metabolomics in Schizophrenia and Major Depressive Disorder