- Maletic-Savatic M, Lenn NJ, Trimmer JS. (1995) Differential spatiotemporal expression of K+ channel polypeptides in rat hippocampal neurons developing in situ and in vitro. J Neurosci 15: 3840-3851. PMID: 7751950
- Maletic-Savatic M, Malinow R. (1998) Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part I: Trans-Golgi network-derived organelles undergo regulated exocytosis. J Neurosci 18: 6803-6813. PMID: 9712651
- Maletic-Savatic M, Koothan T, Malinow R. (1998) Calcium-evoked dendritic exocytosis in cultured hippocampal neurons. Part II: Mediation by calcium/calmodulin-dependent protein kinase II. J. Neurosci. 18: 6814-6821. PMID: 9712652
- Mainen ZF, Maletic-Savatic M, Shi SH, Hayashi Y, Malinow R, Svoboda K. (1999) Two-photon imaging in living brain slices. Methods (San Diego, Calif.) 18: 231-239. PMID: 10356355
- Maletic-Savatic M, Malinow R, Svoboda K. (1999) Rapid dendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity. Science 283: 1923-1927. PMID: 10082466
- Nasr J, Gabis L, Maletic-Savatic M, Andriola M. (2001) The Electroencephalogram in Children with Developmental Dysphasia. Epilepsy and Behav 2: 115-118. PMID: 12609193
- Manganas L, Maletic-Savatic M. (2005) Stem Cell Therapy for CNS Demyelinating Diseases. Curr Neurol Neurosci Rep 5(3): 225-231. PMID: 15865888
- Mignone JL, Roig-Lopez JL, Fedtsova N, Schones DE, Manganas LN, Maletic-Savatic M, Keyes WM, Mills AA, Gleiberman A, Zhang MQ, Enikolopov G. (2007) Neural Potential of a Stem Cell Population in the Hair Follicle. Cell Cycle 6(17): 2161-2170. PMID: 17873521
- Manganas L, Zhang S, Li Y, Hazel R, Smith D, Wagshul M, Henn F, Benveniste H, Djuric P, Enikolopov G, Maletic-Savatic M. (2007) Magnetic Resonance Spectroscopy identifies neural progenitor cells in the live human brain. Science 318: 980-985. PMID: 17991865
- Maletic-Savatic M, Vingara LK, Manganas LM, Li Y, Zhang S, Sierra A, Hazel A, Smith D, Wagshul ME, Henn F, Krupp L, Enikolopov G, Benveniste H, Djuric PM, Pelczer I. (2008) Metabolomics of neural progenitor cells: A novel approach to biomarker discovery. Cold Spring Harb Symp Quant Biol 73: 389-401. PMID: 19022759
- Djuric P, Wagshul M, Henn F, Benveniste H, Enikolopov G, Maletic-Savatic M. (2008) Response to Comments on “Magnetic Resonance Spectroscopy Identifies Neural Progenitor Cells in the Live Human Brain”. Technical Report, Science 321: 640. PMID: 26380846
- Malinow R, Hayashi Y, Maletic-Savatic M, Zaman SH, Poncer JC, Shi SH, Esteban JA, Osten P, Seidenman K. (2010) Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection. Cold Spring Harb Protoc 2010(4): 5406. PMID: 20360360
- Sierra A, Encinas JM, Deudero JJ, Chancey JH, Enikolopov G, Overstreet-Wadiche LS, Tsirka SE, Maletic-Savatic M. (2010) Microglia shape adult hippocampal neurogenesis through apoptosis-phagocytosis coupling. Cell Stem Cell 7(4):483-495. PMID: 20887954
- Ma LH, Li Y, Djurić PM, Maletić-Savatić M. (2011) Systems biology approach to imaging of neural stem cells. Methods Mol Biol 711: 421-434. PMID: 21279615
- Sierra A, Encinas JM, Maletic-Savatic M. (2011) Adult human neurogenesis: from microscopy to magnetic resonance imaging. Front Neurosci 5: 47. PMID: 21519376
- Allen GI, Maletic-Savatic M. (2011) Sparse Non-Negative Generalized PCA with applications to metabolomics. Bioinformatics 27(21): 3029-3035. PMID: 21930672
- Yu HJ, Christodoulou C, Bhise V, Greenblatt D, Patel Y, Serafin D, Maletic-Savatic M, Krupp LB, Wagshul M. (2012) Multiple white matter tract abnormalities underlie cognitive impairment in RRMS. Neuroimage 59(4): 3713-3722. PMID:22062194
- Abraham AB, Bronstein R, Reddy AS, Maletic-Savatic M, Aguirre A, Tsirka SE. (2013) Aberrant neural stem cell proliferation and increased adult neurogenesis in mice lacking chromatin protein HMGB2. PLos One 8(12): e84838. PMID: 24391977
- Abraham AB, Bronstein R. Chen EI, Koller A, Ronfani L, Maletic-Savatic M, Tsirka SE. (2013) Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells. Proteome Sci 11(1): 18. PMID: 23621913
- Allen GI, Peterson C, Vannucci M, Maletic-Savatic M. (2013) Regularized partial least squares with an application to NMR spectroscopy. Stat Anal Data Min 6(4): 302-314. PMID: 24511361
- Wiszniewski W, Hunter JV, Hanchard NA, Willer JR, Shaw C, Tian Q, Illner A, Wang X, Cheung SW, Patel A, Campbell IM, Gelowani V, Hixson P, Ester AR, . . . Maletic-Savatic M, Rosenfeld JA, Shaffer LG, Davis EE, Belmont JW, Dunstan S, Simmons CP, Bonnen PE, Leal SM, Katsanis N, Lupski JR, Lalani SR. (2013) TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. Am J Hum Genet, 93(2): 197-210. PMID: 23810381
- Peterson C, Vannucci M, Karakas C, Choi W, Ma L, Maletic-Savatic M. (2013) Inferring metabolic networks using the Bayesian adaptive graphical lasso with informative priors. Stat Interface 6: 547-558. PMID: 24533172
- (fix)Vingara LK, Yu HJ, Wagshul ME, Serafin D, Christodoulou C, Pelczer I, Krupp LB, Maletic-Savatic M. (2013) Metabolomic approach to human brain spectroscopy identifies associations between clinical features and the frontal lobe metabolome in multiple sclerosis. Neuroimage 82: 586-594. PMID: 23751863
- Pati S, Supeno NE, Muthuraju S, Abdul Hadi R, Ghani AR, Idris FM, Maletic-Savatic M, Abdullah JM, Jaafar H. (2014) MicroRNA profiling reveals unique miRNA signatures in IGF-1 treated embryonic striatal stem cell fate decisions in striatal neurogenesis in vitro. Biomed Res Int 2014: 503162. PMID: 25254208
- Shetty AN, Chiang S, Vannucci M, Maletic-Savatic M, Lee W. (2014) Spatial Mapping of Translational Diffusion Coefficients Using Diffusion-Tensor Imaging: A Mathematical Description. Concepts in Magnetic Resonance, Part A 43 (1): 1-27. PMID: 27441031
- Botas A, Cambell-Moore H, Han X, Maletic-Savatic M. (2015) Metabolomics of neurodegenerative diseases. Inter Rev Neurobiol 122: 53-80. PMID: 26358890
- A. Erramuzpea, J.M. Encinas, A. Sierra, M. Maletic-Savatic, A.L. Brewster, A.E. Anderson, S. Stramaglia, J.M. Cortes. (2015) Longitudinal variations of brain functional connectivity in a mouse model of mesial temporal lobe epilepsy. F1000Research 4: 144. PMID: 26167275
- Arnold JM, Choi WT, Sreekumar A, Maletić-Savatić M. (2015) Analytical strategies for studying stem cell metabolism. Front Biology 10 (2): 141-153. PMID: 26213533
- Sierra A, Martín-Suárez S, Valcárcel-Martín R, Pascual-Brazo J, Aelvoet S-A, Abiega O, Deudero JJP, Brewster AL, Bernales A, Anderson AE, Baekelandt V, Maletić-Savatić M*, Encinas JM* (2015) Neuronal Hyperactivity Accelerates Depletion of Neural Stem Cells and Impairs Hippocampal Neurogenesis. Cell Stem Cell 16 (5) 488-503. * Co-senior authors PMID: 25957904
- Zhu Y, Fan Q, Han X, Zhang H, Chen J, Wang Z, Zhang Z, Tan L, Xiao Z, Tong S, Maletic-Savatic M, Li Y. (2015) Decreased thalamic glutamate level in un-medicated adult obsessive-compulsive disorder patients detected by proton magnetic resonance spectroscopy. J Affect Disord 178: 193-200. PMID: 25819113
- Pati S, Muthuraju S, Hadi RA, Huat TJ, Singh S, Maletic-Savatic M, Abdullah JM, Jaafar H. (2016) Neurogenic plasticity of mesenchymal stem cell, an alluring cellular replacement for traumatic brain injury. Curr Stem Cell Res Ther 11(2): 149-157. PMID: 26763886
- (fix)Irungu-Mwangi B, Cao B, Tustison NJ, Kochunov P, Maletic-Savatic M, Frye RE, Soares JC, Hasan K. (2016) Entorhinal Cortex Thickness across the Human Lifespan. J Neuroimaging 26(3): 278-82. PMID: 26565394
- Abiega O, Beccari S, Diaz-Aparicio I, Nadjar A, Layé S, Leyrolle Q, Gómez-Nicola D, Perry HV, Sánchez-Zafra V, Deudero JJP, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco M, Matute C, Maletic-Savatic M, Encinas JM, Sierra A. (2016) Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling. PLoS Biol 14(5):e1002466. PMID:27228556
- Zhang X, Tang Y, Maletic-Savatic M, Sheng J, Zhang X, Zhu Y, Zhang T, Wang J, Tong S, Wang J, Li Y. (2016) Altered neuronal spontaneous activity correlates with glutamate concentration in medial prefrontal cortex of major depressed females: An fMRI-MRS study. J Affect Disord 201: 153-161. PMID: 27235818
- Cvoro A, Bajic A, Zhang A, Simon M, Sieglaff DH, Maletic-Savatic M, Korac A, Webb P. (2016) Ligand independent and subtype-selective actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells. PlosOne 11(10):e0164407. PMID: 27732649
- Petrovchich I, Sosinsky A, Konde A, Archibald A, Henderson D, Maletic-Savatic M, Milanovic S (2016). Metabolomics in Schizophrenia and Major Depressive Disorder. Front Biol, 11(3): 222-231. PMID in process
- Semerci F, Maletic-Savatic M (2016).Transgenic mouse models for studying adult neurogenesis. Front Biol. 11(3): 151-167. PMID: 28473846
- Basch M, Brown R, Jen HI, Semerci F, Depreux F, Edlund R, Zhang H, Norton C, Gridley T, Cole S, Doetzlhofer A, Maletic-Savatic M, Segil N, Groves A. (2016) Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. eLife 5. pii: e19921. PMID: 27966429
- Jiang X, Chen J, Bajić A, Zhang C, Song X, Carroll SL, Wang MC, Xue M, Schaaf C, Maletić-Savatić M, Wang J. (2017) Quantitative Real-Time Imaging of Glutathione. Nat Commun. 8: 16087. PMID: 28703127
- Maletic-Savatic M. (2017) A question of fate. PLoS Biol. 15(5):e2002329. PMID: 28505150
- Bielefeld P, Sierra A, Encinas JM, Maletic-Savatic M, Anderson A. A, Fitzsimons CP. (2017) Standardized Protocol for Stereotaxic Intrahippocampal Administration of Kainic Acid Combined with Electroencephalographic Seizure Monitoring in Mice. Front Neurosci. 11:160. PMID: 28405182
- Semerci F, Choi WT, Bajic A, Thakkar A, Encinas JM, Depreux F, Segil N, Groves AK, Maletic-Savatic M. (2017) Lunatic fringe-mediated Notch signaling regulates adult hippocampal neural stem cell maintenance. eLife 6. pii: e24660. PMID: 28699891
- Li B, Sierra A, Deudero JJ, Semerci F, Laitman A, Kimmel M*, Maletic-Savatic M* (2017) Multitype Bellman-Harris branching model provides biological predictors of early stages of adult hippocampal neurogenesis. *Co-senior authors; BMC Syst Biol. 11(Suppl 5):90. doi: 10.1186/s12918-017-0468-3. PMID: 28984196
- Liu L, MacKenzie KR, Putluri N, Maletic-Savatic M, Bellen HJ. (2017) The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. Cell Metab. 26(5):719-737.e6. doi: 10.1016/j.cmet. 2017.08.024. PMID: 28965825
- Gandy K, Kim S, Sharp C, Dindo L, Maletic-Savatic M*, Calarge C.* (2017) Pattern Separation: A Potential Marker of Impaired Hippocampal Adult Neurogenesis in Major Depressive Disorder. * Co-senior authors. Front Neurosci. 11:571. doi: 10.3389/fnins.2017. 00571. eCollection 2017. PMID: 29123464
- Beccari S, Valero J, Maletic-Savatic M, Sierra A. (2017) A simulation model of neuroprogenitor proliferation predicts age-related loss of hippocampal neurogenesis but not astrogenesis. Sci Rep. 7 (1):16528 doi: 10.1038/s41598-017-16466-3. PMID: 29184142
- Tang C, Chen K, Bajic A, Choi WT, Baluya DL, Maletic-Savatic M. (2018) Analytical platforms and techniques to study stem cell metabolism. Methods Mol Biol 1842:265-281. PMID: 30196417
- Murthy KLP, Srinivasan T, Bochter MS, Xi R, Varanko AK, Tung KL, Semerci F, Xu K, Maletic-Savatic M, Cole SE, Shen X. Radical and lunatic fringes modulate notch ligands to support mammalian intestinal homeostasis. Elife. 2018 Apr 9;7. pii: e35710. doi: 10.7554/eLife.35710. PMID: 29629872
- Choi WT*, Tosun M*, Jeong HH*, Karakas C, Semerci F, Liu Z, Maletić-Savatić M. (2018) Metabolomics of Mammalian Brain Reveals Regional Differences. BMC Systems Biology, 12 (Suppl 8):127. PMID: 30577853
- Jiang X, Zhang C, Chen J, Choi S, Zhou Y, Zhao M, Song X, Chen X, Maletic-Savatic M, Palzkill T, Moore D, Wang M, Wang J. (2019) Quantitative Real-Time Imaging of Glutathione with Sub-Cellular Resolution. Antioxid Redox Signal. 30 (16):1900-1910. PMID: 30358421
- Chen K, Baluya D, Tosun M, Li F, Maletic-Savatic M. (2019) Imaging Mass Spectrometry: A New Tool to Assess Molecular Underpinnings of Neurodegeneration. Metabolites. 10;9 (7). PMID: 31295847
- Lucassen PJ, van Dam AMW, Kandel P, Bielefeld P, Korosi A, Fitzsimons CP, Maletic-Savatic M. (2019) The orphan nuclear receptor TLX: an emerging master regulator of cross-talk between microglia and neural precursor cells. Neuronal Signal 3(2): NS20180208. PMID: 32271856
- Tosun M, Semerci F, Maletic-Savatic M. (2019) Heterogeneity of Stem Cells in the Hippocampus, Adv Exp Med Biol 1169; 31-53. PMID: 31487017
- Lucassen PJ, Fitzsimons CP, Salta E, Maletic-Savatic M. (2020) Adult neurogenesis, human after all (again): Classic, optimized, and future approaches. Behav Brain Res 381; 112458-112462. PMID 31899214
- Diaz-Aparacio I, Paris I, Sierra-Torre V, Piaza-Zabala A, Rodriguez-Iglesias N, Marquez-Ropero M, Beccari S, Abiega O, Alberdi E, Matute C, Bernales I, Schulz A, Otrokocsi L, Sperlagh B, Happonen KE, Lemke G, Maletic-Savatic M, Valero J, Sierra A (2020) Microglia actively remodels adult hippocampal neurogenesis through the phagocytosis secretome. J Neurosci. 40(7): 1453–1482. PMCID: PMC7044727
- MacKenzie KR, Zhao M, Barzi M, Wang J, Bissig KD, Maletic-Savatic M, Jung SY, Li F (2020) Metabolic profiling of norepinephrine reuptake inhibitor atomoxetine. Eur J Pharm Sci. 153:105488. PMID: 32712217
- Semerci F, Parkitny L, Maletic-Savatic M. (2021) Mouse models for studying hippocampal adult neural stem cell biology, Mouse Genetics: Methods and Protocols, 2nd edition, Springer. 2224:61-74. PMID: 33606206
- Manganas LN, Durá I, Osenberg S., Semerci F., Tosun M., Mishra R., Parkitny L., Encinas JM, Maletic-Savatic M (2021). BASP1 Labels Neural Stem Cells in the Neurogenic Niches of Mammalian Brain. Sci Rep. 11(1):5546. PMID: 33692421
- Parkitny L, Maletic-Savatic M.Glial PAMPering and DAMPening of Adult Hippocampal Neurogenesis. Brain Sci. 2021 Sep 29;11(10):1299. doi: 10.3390/brainsci11101299. PMID: 34679362
- Valenzuela M, Bartres-Faz D, Bullmore E, Fjell A, Maletic-Savetic M, Martins R, Solowij N, Yücel M. (2013) More thinking about less data: a perspective from the 2nd Provence Summer Workshop. Mol Psych 18(5): 524-525. PMID: 23478747
- Maletic-Savatic M, Valenzuela M (2016). Adult neurogenesis in Provence: Where history meets science. Front Biol, 11(3): 149-150.
- Sahin M, Jones SR, Sweeney JA, Berry-Kravis E, Connors BW, Ewen JB, Hartman AL, Levin AR, Potter WZ, Mamounas LA. and the Biomarker Workshop Faculty (2018) Discovering translational biomarkers in neurodevelopmental disorders. Nat Rev Drug Discov. Dec 20, PMID: 30936503
- Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Jiménez-Panizo A, Chamakuri S, Raji IO, Chang L, Fuentes-Prior P, MacKenzie KR, Benn CL, Estébanez-Perpiñá E, Venken K, Moore DD, Young DW, Maletic-Savatic M. (2022) Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 119(13):e2023784119 PMID: 35333654
- Spruill ML, Maletic-Savatic M, Martin H, Li F, Liu X. (2022) Spatial analysis of drug absorption, distribution, metabolism, and toxicology using mass spectrometry imaging. Biochem Pharmacol. 201:115080. PMID: 35561842
- McNerlin, C., Guan, F., Bronk, L., Lei, K., Grosshans, D., Young, D. W., Gaber, M. W., & Maletic-Savatic, M. (2022). Targeting hippocampal neurogenesis to protect astronauts’ cognition and mood from decline due to space radiation effects. Life Sciences in Space Research, 35, 170–179. https://doi.org/10.1016/j.lssr.2022.07.007
- Bokhari, R. S., Beheshti, A., Blutt, S. E., Bowles, D. E., Brenner, D., Britton, R., Bronk, L., Cao, X., Chatterjee, A., Clay, D. E., Courtney, C., Fox, D. T., Gaber, M. W., Gerecht, S., Grabham, P., Grosshans, D., Guan, F., Jezuit, E. A., Kirsch, D. G., … Donoviel, D. (2022). Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. Life Sciences in Space Research, 35, 105–112. https://doi.org/10.1016/j.lssr.2022.08.003
- Wang L, Maletic-Savatic M, Liu Z (2022) Region-specific denoising identifies spatial co-expression patterns and intra-tissue heterogeneity in spatially resolved transcriptomics data. Nat Commun. 13(1):6912. PMID: 36376296
- Sun J, Osenberg S, Irwin A, Ma LH, Lee N, Xiang Y, Li F, Wan YW, Park IH, Maletic-Savatic M*, Ballas N* (2023) Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular features of human astrocytes during their maturation, Cell Rep. 42(1):111942. PMID: 36640327
Neurogenic plasticity of mesenchymal stem cell, an alluring cellular replacement for traumatic brain injury
Metabolomics in Schizophrenia and Major Depressive Disorder