Neuronal hyperactivity impairs neuronal regeneration by accelerating the loss of neural stem cells

Adult neurogenesis is the process of generating new neurons which integrate into existing circuits even after fetal and early postnatal development has ceased. Until recently, it was commonly thought that neurogenesis stops at the end of development. However, in the last decade, many studies have clearly demonstrated that in most mammals including humans, neurogenesis continues in the adults as well but is limited to the specific brain regions, such as hippocampus. …http://www.nri.texaschildrens.org/faculty_research/mirjana_cellstemcell.aspx